• Indications and Usage

    • For the active immunisation of adults and children >2 years against meningococcal meningitis caused by meningococci of serogroups A, C, W135 and Y.
  • Dosage and Administration

    For intramuscular (i.m.) injection.

    • The recommended dose of the vaccine contained in 0.5 mL must be administered.
    • In adults and children >5 years, immunity will persist for up to 3 years.
    • Children who were aged <5 years when first vaccinated should be considered for revaccination after 2-3 years if they remain at high risk
  • Dosage Forms and Strengths

    Each 0.5-mL dose of the reconstituted vaccine contains 50 mcg of each of the purified polysaccharides from Neisseria meningitidis (meningococcus) of serogroups A, C, W135 and Y. Mencevax ACWY also contains sucrose and trometamol as excipients; the diluent contains sodium chloride, water for injections (and phenol for multidose presentations).

  • Contraindications

    • Hypersensitivity to any component of the vaccine.
  • Warnings and Precaution

    • Appropriate medical treatment and supervision should always be readily available in cases of a rare anaphylactic reaction following administration of the vaccine.
    • As with other vaccines, the administration of Mencevax ACWY should be postponed in subjects suffering from acute severe febrile illness. However, the presence of a minor infection eg, cold, should not result in the deferral of vaccination.
    • Mencevax ACWY will only confer protection against Neisseria meningitidis serogroups A, C, W135 and Y. As for any vaccine, complete protection cannot be guaranteed in every vaccinated individual.
    • If administered to subjects with impaired immune responses, the vaccine may not induce an effective response.
  • Adverse Reactions

    • Common: Loss of appetite, gastrointestinal symptoms eg, nausea, vomiting and diarrhoea, myalgia, swelling at the injection site, fever.
    • Very Common: Irritability, drowsiness, headache, pain and redness at the injection site, fatigue,
    • Uncommon: Dizziness.
    • Others: Urticaria, rash, angioneurotic oedema, arthralgia, musculoskeletal stiffness, influenza-like symptoms, chills
  • Use in Specific Populations

    • For pregnant and lactating, Mencevax should only be used when clearly needed.